Cervical cancer in Seychelles

Cervical carcinoma is a most common cancer of women in Seychelles. Since 1983; Papanicolaou smear diagnosis of cytological specimens of cervix has been carried out. The recent observation is that the incidence of cervical carcinoma is decreasing. With the data on all the cases of cervical carcinoma diagnosed by histopathological examination from 1986 to 1995 in the Republic of Seychelles and demographic data in the same period; a simple epidemiological study of cervical carcinoma was made. Mean age of occurrence for cervico intra-ephithelial neoplasia (CIN) III; microinvasive carcinoma; invasive squamous cell carcinoma and adenocarcinoma were respectively 39.8; 40.9; 56.2; 52 years; the annual incidences were 64.3; 17.4; 39.8 and 9.2 per 100;000 women aged 20 years above. It appears that the incidence of cervical cancer has declined over the last decade

Rupture of dissecting aneurysm: autopsy study of 3 cases

Dissecting aneurysm (DA); more appropriately termed dissecting haematoma; is the separation of layers of the vascular wall by a column of blood from the lumen. Dissecting aneurysms of the aorta differ from atherosclerotic and syphilitic aneurysms in that they are not usually associated with marked dilatation of the aorta. DA of the aorta; irrespective of the etiology; if untreated; are associated with a rapidly fatal outcome in 75 per cent to 90 per cent of the patients. Death from DA most often results from rupture. Rupture sites frequently associated with a fatal outcome include the pericardial sac leading to acute haemopericardium; the mediastinum; the left pleural cavity and the retroperitoneum. Autopsy study on three cases of sudden death revealed haemopericardium as a result of rupture of DA of the ascending aorta. One case was seen in a young individual with Marfan's syndrome and two were present in elderly individuals with hypertension. The etiopathogenesis; presentation; outcome and management of this fatal complication is discussed

Trend of cervical cancer in Seychelles

A 10-year study of all cervical biopsies and hysterectomy specimens received in the Department of Pathology; Victoria Hospital was carried out. Representative punch biopsies of cervix; either colposcope guided; or taken from non-staining areas of cervix following application of Schiller's iodine paint; and fixed in 10 per cent formal saline in the theatre were received in the pathology department. During the ten year period (1983-1992); 175 cases of cervical cancer were detected. Of these; 66 cases were at the CIN 3 stage; 28 were CIN 3 with microinvasion; 69 cases showed frank infiltrating squamos cell carcinoma; 11 exhibited adenocarcinoma and 1 had adenosquamous features

Clinicopathology study of oral and oropharyngeal carcinoma in Seychelles

Oral and oropharyngeal carcinoma happens to be one of the commonest cancerous lesions in Seychelles. According to cancer registry statistics; of 621 cases of cancer from 1983 to 1991; oral and oropharyngeal carcinoma account for 9.98 per cent of all cases. An attempt has been made to analyse the age and sex of patients; the location and morphology of the carcinomas; and the prognosis; so as to present the clinicopathological features of oral and oropharyngeal carcinoma in Seychelles; with possible etiological factors

Pseudosarcoma in marfan's syndrome : a case study

Pseudosarcomatous fasciitis was reported by Knowaler et al in 1955. It is a benign and quasi-neoplastic proliferation of fibroblasts; which is often mistaken for a sarcoma because of its rapid growth; rich cellularity and mitotic activity. It is one of the more common soft tissue lesions and exceeds in frequency other tumor or tumor-like lesions of fibrous tissue. This attested to by the more than 1000 cases that were reviewed at the American Armed Forces Institute of Pathology (AFIP) in a 20 year period. The case of pseudosarcoma occuring in a patient with marfan's syndrome in Seychelles is reported

Non-cancerous breast lesions in Seychelles : an appraisal

In recent years there has been an increase in the number of both cancerous and non-cancerous lesions of the breast seen by doctors in Seychelles. The cancer registry held by the department of pathology reveals that 3 cases of breast cancer were reported in 1989; 4 in 1990; 6 in 1991 and 11 in 1992. Department of pathology records also reveal that 36 cases of non-cancerous breast lesions were reported in 1989; 30 in 1990; 48 in 1991 and 49 in 1992. These increases call for the development of a protocol for the management of all the palpable; nodular swellings of the breast; irrespective of marital status; age; parity and use of oral contraceptives